Intro to Interstitial Cystitis

Interstitial cystitis (in-tur-STISH-ul sis-TIE-tis) — also called painful bladder syndrome — is a chronic condition in which you experience bladder pressure, bladder pain and sometimes pelvic pain, ranging from mild discomfort to severe pain.

Your bladder is a hollow, muscular organ that stores urine. The bladder expands until it's full and then signals your brain that it's time to urinate, communicating through the pelvic nerves. This creates the urge to urinate for most people. With interstitial cystitis, these signals get mixed up — you feel the need to urinate more often and with smaller volumes of urine than most people.

 

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What are the symptoms of Interstitial cystitis?

The signs and symptoms of interstitial cystitis vary from person to person. If you have interstitial cystitis, your symptoms may also vary over time, periodically flaring in response to common triggers, such as menstruation, sitting for a long time, stress, exercise and sexual activity.

Interstitial cystitis signs and symptoms include:

  • Pain in your pelvis or between the vagina and anus in women or between the scrotum and anus in men (perineum).
  • Chronic pelvic pain.
  • A persistent, urgent need to urinate.
  • Frequent urination, often of small amounts, throughout the day and night. People with severe interstitial cystitis may urinate as often as 60 times a day.
  • Pain or discomfort while the bladder fills and relief after urinating.
  • Pain during sexual intercourse.

The severity of symptoms caused by interstitial cystitis often varies, and some people may experience periods during which symptoms disappear.

Although signs and symptoms of interstitial cystitis may resemble those of a chronic urinary tract infection, urine cultures are usually free of bacteria. -However, symptoms may worsen if a person with interstitial cystitis gets a urinary tract infection.

What causes Interstitial Cystitis?

The exact cause of interstitial cystitis isn't known, but it's likely that many factors are at play. For instance, people with interstitial cystitis may also have a defect in the protective lining (epithelium) of the bladder. A leak in the epithelium may allow toxic substances in urine to irritate your bladder wall.

Other suggested but unproven factors that may contribute to interstitial cystitis include an autoimmune reaction, heredity, infection or allergy.